A pharmacological review on intraperitoneal chemotherapy for peritoneal malignancy
نویسندگان
چکیده
منابع مشابه
A systematic review on the efficacy of cytoreductive surgery combined with perioperative intraperitoneal chemotherapy for diffuse malignancy peritoneal mesothelioma.
BACKGROUND In the past, diffuse malignant peritoneal mesothelioma (DMPM) was regarded as a preterminal condition. The length of survival was dependent upon the aggressive versus indolent biologic behavior of the neoplasm. The overall median survival was approximately 1 year after systemic chemotherapy. Cytoreductive surgery (CRS) combined with perioperative intraperitoneal chemotherapy (PIC) ha...
متن کاملIs Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy a Safe and Effective Procedure for Treating Patients With a Peritoneal Surface Malignancy?
Multimodality therapy, such as a combination of cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC), is associated with improved survival for selected patients with peritoneal metastasis of various cancer types. Despite this, this procedure is not widely accepted due to its high rates of morbidity and mortality. In several studies on the combined use of CRS and HIP...
متن کاملPeritoneal Malignancy in Children: A Pictorial Review.
Peritoneal malignancies are a rare occurrence in children, often metastatic and rarely originating primarily in the peritoneum. The imaging findings of these entities in the pediatric age have not been recently reviewed or they have been previously described or depicted mostly as part of articles discussing each entity separately. This is a review of the most relevant peritoneal malignancies in...
متن کاملEarly postoperative intraperitoneal chemotherapy as an adjuvant therapy to surgery for peritoneal carcinomatosis from gastrointestinal cancer: pharmacological studies.
Gastrointestinal malignancy may spread to peritoneal surfaces in the absence of lymphatic or hematogenous metastases. To treat peritoneal carcinomatosis, a uniformly lethal disease process, extensive cytoreductive surgery and i.p. chemotherapy were combined. Early postoperative i.p. chemotherapy was instilled in the first few days after the surgical procedure in an attempt to treat anatomic sit...
متن کامل[Peritoneal gistosis: role of cytoreductive surgery and perioperative intraperitoneal chemotherapy].
Gastrointestinal stromal tumors (GIST) are the most frequent mesenchymal neoplasms of the digestive tract. They are usually seen in patients over the age of 50, with equal sex distribution, with an annual incidence of approximately 5000 in the U.S. They originate from cells of Cajal and the most frequent location is the stomach (60%), followed by the jejunum and ileum (30%). Although they frequ...
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ژورنال
عنوان ژورنال: World Journal of Gastrointestinal Oncology
سال: 2010
ISSN: 1948-5204
DOI: 10.4251/wjgo.v2.i2.109